Oxindole derivative
AssigneeTaiho Pharmaceutical Co., Ltd.
InventorsAkihiro Kawaguchi, Atsushi Sato, Makoto Kajitani, Mitsugi Yasumoto, Junji Yamamoto
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AssigneeTaiho Pharmaceutical Co., Ltd.
InventorsAkihiro Kawaguchi, Atsushi Sato, Makoto Kajitani, Mitsugi Yasumoto, Junji Yamamoto
Estimating the term…
The present invention provides an oxindole derivative which has the following formula and is useful as medicaments for treating senile dementia, i.e., as cerebral function improving agents and cerebral metabolism activators or anoxic brain damage protectives ##STR1## wherein R.sup.1 is hydrogen atom, halogen atom, lower alkyl group or lower alkoxyl group, R.sup.2 is hydrogen atom or lower alkyl group, R.sup.3 is --CH.sub.2 --R.sup.5 group (R.sup.5 being alkyl group which may form a ring; benzodioxanyl group; or phenyl group which may have plural substituents selected from among halogen atom, lower alkyl group, lower alkoxyl group, hydroxyl group, diethylamino group, trifluoromethyl group, nitrile group, nitro group and benzyloxy group), R.sup.2 and R.sup.3 may form together .dbd.CH--R.sup.5 (R.sup.5 being same as above), R.sup.4 is 1-propylbutyl group; pyridyl group; or phenyl group which may be substituted by lower alkoxyl group, halogen atom, diethylamino group, benzyloxy group, trifluoromethyl group, nitrile group, nitro group or lower alkyl group.
An oxindole derivative represented by the formula ##STR124## wherein R.sup.1 is hydrogen atom, halogen atom, lower alkyl group or lower alkoxyl group, R.sup.2 is hydrogen atom or lower alkyl group, R.sup.3 is --CH.sub.2 --R.sup.5 group, R.sup.5 is lower alkyl;
Dependencies are inferred from the claim text.