.beta.-carbonyl-carboxyamides of 1,3-thiazolidines

Abstract

This application relates to compounds of formula I; ##STR1## wherein R is hydrogen, a linear or branched C.sub.1 -C.sub.4 -alkyl, allyl or propargyl; X is O, CH.sub.2 or S; R.sub.1 is --(CH.sub.2).sub.n Ra, hydroxy, --O--(CH.sub.2).sub.n Ra, --NRbRc or --NH c(CH.sub.2).sub.m --NRbRc; Ra is hydrogen, a linear or branched C.sub.1 -CH.sub.4 -alkyl, phenyl, p-methoxy-phenyl, 3,4,5-trimethoxyphenyl, B-pyryidyl, cyclopentyl or cyclohexyl; Rb and Rc, can be the same or different and are selected independently in the group of hydrogen, linear or branched C.sub.1 -C.sub.4 -alkyl, cyclohexyl, cyclopentyl, benzyl, hexahydrobenzyl, .alpha.,.beta. or .gamma.-pyridylmethyl; or Rb and Rc taken together with the N atom to which they are bound can form a morpholino, piperidino or piperazino residue of formula Rd--N(CH.sub.2 --CH.sub.2).sub.2 --N-- wherein Rd is hydrogen, linear or branched C.sub.1 -C.sub.4 -alkyl, benzyl, hexahydrobenzyl, (C.sub.6 H.sub.5).sub.2 CH--, (p--F--C.sub.6 H.sub.4).sub.2 CH or B-pyridylmethyl; n is zero or an integer from 1 to 3 and m is 2 or 3; and a process for the preparation thereof.

Dependencies are inferred from the claim text.