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US 5,206,250 AGranted
Bis-naphthalimides containing amide and thioamide linkers as anticancer agents
AssigneeThe Du Pont Merck Pharmaceutical Company
InventorJung-Hui Sun
Life of this patent
Estimating the term…
Abstract
There are provided novel bis-naphthalimide compounds useful as antitumor agents, pharmaceutical compositions containing them and processes for preparing such compounds.
Claims8
A compound of the formula:
- ##STR12## or a diastereomerically pure or racemate or a mixture of racemate and meso, pharmaceutically acceptable salts thereof, wherein:
- ##STR13## each R.sup.1 and R.sup.4 independently are H, CH.sub.3 or CH.sub.2 CH.sub.3 ;
- R.sup.2 and R.sup.3 are H;
- each A independently is O or S;
- XS and Y independently are H or NO.sub.2,
- each p is 0;
- n is 2 or 3.
4 more elements
Dependencies are inferred from the claim text.