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US 5,206,222 AGranted
Methods for the reduction of myocardial reperfusion injury
AssigneeVanderbilt University
InventorsMervyn B. Forman, Edwin K. Jackson
Life of this patent
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Abstract
This invention relates to a method to treat a heart attack victim to reduce heart muscle damage. In particular, the invention relates to a met Grant Statement This research was supported in part by the National Institute of Health, Grant R01 HL40892-01.
Claims8
The method to reduce myocardial reperfusion injury in a patient without causing a hypotensive reaction comprising:
- A) coadministering between 0.03 .mu.g/kg/min. to 30 .mu.g/kg/min. of adenosine or an analogue thereof and an effective dose of lidocaine.
The method to reduce myocardial reperfusion injury in a patient without causing a hypotensive reaction comprising:
- (a) coadministering between 0.03 .mu.g/kg/min. to 3 .mu.g/kg/min. of adenosine-1 receptor agonist and an effective dose of lidocaine.
The method to reduce myocardial reperfusion injury in a patient without causing a hypotensive reaction comprising:
- (a) coadministering between 0.03 .mu.g/kg/min. to 30 .mu.g/kg/min. of adenosine-2 receptor agonist and an effective dose of lidocaine.
Dependencies are inferred from the claim text.