Reducing post-prandial fluctuations in plasma concentrations of large neutral amino acids (LNAA)
AssigneeInterneuron Pharmaceuticals, Inc.
InventorsRichard J. Wurtman, Judith J. Wurtman
Life of this patent
Estimating the term…
Abstract
Methods of reducing post-prandial fluctuations in plasma levels of large, neutral amino acids (LNAA), as well as compositions useful in that method. The foods and compositions comprise a carbohydrate to protein ratio of from about 3:1 to about 6:1 and, in a specific embodiment, a ratio of 4:1, which results in minimizing the variability in responses individuals exhibit to drugs which are LNAA.
Claims8
A composition for administration to an individual to reduce fluctuations in plasma large neutral amino acid (LNAA) levels, comprising a ratio of carbohydrate to protein of approximately 3:1 to approximately 6:1.
A method of reducing post-prandial fluctuations in plasma concentrations of LNAA, comprising administering to an individual an effective quantity of a composition comprising a ratio of carbohydrate to protein of from approximately 3:1 to approximately 6:1.
A method of reducing post-prandial fluctuations in plasma concentrations of LNAA, comprising administering to an individual foods which provide a ratio of carbohydrate to protein of from approximately 3:1 to approximately 6:1.
A method of reducing post-prandial fluctuations in plasma concentration of LNAA comprising administering to an individual foods which provide approximately 20-27 grams of protein per meal or approximately 5-6 grams of protein per snack and approximately 87-116 grams of carbohydrate per meal or approximately 25-29 grams of carbohydrate per snack.
Dependencies are inferred from the claim text.