Film-forming composition and use for coating pharmaceuticals, foods and the like
AssigneeFMC Corporation
InventorsThomas A. Wheatley, Clayton I. Bridges, Jr., Carl R. Steuernagel
Life of this patent
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Abstract
A water-dispersible, particulate film-forming composition is produced by blending a mixture of particles of water-soluble cellulose acetate; pigment particles, a plasticizer for the water-soluble cellulose acetate, and a surfactant. The composition is useful as a film-forming material for coating solid pharmaceutical forms.
Claims15
A water-dispersible, particulate film-forming composition for use in film coating solid pharmaceutical dosages comprising a dry mixture produced by dry blending on a 100% weight basis in an amount of from about 50% to about 90%
- particles of water-soluble cellulose acetate
- pigment particles in an amount from about 0% to about 20%
- a plasticizing amount of plasticizer in an amount from about 2% to about 40% for the water-soluble cellulose acetate, and
- a surfactant in an amount from about 0.2% to about 2.0% which can be a separate component or a plasticizer having surfactant properties.
A solid pharmaceutical or food dosage form comprising a matrix containing a pharmaceutically active or nutrient material, and a coating thereover, the coating comprising on a 100% weight basis a dry blended mixture of particles of water-soluble cellulose acetate in an amount of from about 50% to about 90%;
- pigment particles in an amount from about 0% to about 20%;
- a plasticizer for the water-soluble cellulose acetate in an amount from about 2% to 40%.
A water-dispersible, particulate film-forming composition for use in film coating solid pharmaceutical dosages comprising a dry mixture produced by dry blending from about 50% to about 90% of water-soluble cellulose acetate particles;
- from about 2% to about 40% of a polyethylene glycol having a molecular weight of 400 as plasticizer for the water-soluble cellulose;
- from about 0% to about 20% of titanium dioxide pigment particles, and from about 0.2% to about 2.0% of dioctyl sodium sulfosuccinate surfactant.
Dependencies are inferred from the claim text.