Cream containing aluminum potassium sulfate and process for preparing same
AssigneeFlorin Vegyipari Szovetkezet
InventorsErno Orban, Peter Varnai
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Abstract
The invention relates to a novel oil-in-water type cream containing aluminum potassium sulfate, which is useful for the treatment of varicosity. The composition of the invention contains 1 to 15% by weight of pharmaceutically acceptable lipid-type ointment base, 0 to 10% by weight of aluminum potassium sulfate dissolved in water, 10 to 80% by weight of propylene glycol and 0.1 to 5.0% by weight of cetyltrimethylammonium bromide and/or cetyltrimethylammonium chloride as emulsifying agent.
Claims8
An oil-in-water (o/w) cream composition containing aluminum potassium sulfate for therapeutical use which comprises:
- 10 to 80% by weight an oily phase of pharmaceutically acceptable lipid ointment bases, and
- 20 to 90% by weight of an aqueous phase comprising 1 to 15% by weight of dissolved aluminum potassium sulphate, 0 to 10% by weight of propylene glycol, 0.1 to 5.0% by weight of cetyltrimethylammonium bromide, cetyltrimethylammonium chloride or mixtures thereof and water, calculated from the total weight of the cream composition.
The cream composition of 1, which comprises 3 to 7% by weight of aluminum potassium sulfate dissolved in the aqueous phase.
A process for the preparation of an oil-in-water (o/w) cream containing aluminum potassium sulfate for therapeutical use which comprises:
- 10to 80% by weight an oily phase of pharmaceutically acceptable lipid ointment bases, and
- 20 to 90% by weight of an aqueous phase comprising 1 to 15% by weight of dissolved aluminum potassium sulphate, 0 to 10% by weight of propylent glycol, 0.1 to 5.0% by weight of cetyltrimethylammonium bromide, cetyltrimethylammonium chloride or mixtures thereof and water, calculated from the total weight of the cream,
- which process comprises dissolving the aluminum potassium sulfate and the cetyltrimethylammonium bromide, cetyltrimethylammonium chloride or mixtures thereof in water, optionally containing propylene glycol, and mixing the solution thus obtained with the pharmaceutically acceptable lipid ointment base.
Dependencies are inferred from the claim text.