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US 5,204,325 AGranted
Viscoelastic solution
OwnerRichard L. Lindstrom, Debra Skelnikinventors
Life of this patent
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Abstract
Viscoelastic solution including a buffered solution, 0.01-8% chondroitin sulfate, 0.1-8% hydroxypropyl methylcellulose, pH adjusted to 6.0-8.0 at a osmolality between 200-400 mOsmol/L. The buffered solution can be HEPES buffered minimum essential media (MEM), phosphate buffer saline (PBS), buffered balanced salt solution, or TC199. A cell growth factor or cell growth supplement is included in the solution.
Claims6
A viscoelastic composition comprising:
- a. a buffered balanced salt solution;
- b. hydroxypropyl methyl cellulose;
- and,
- c. a glycosaminoglycan which is dermatin sulfate, heparin sulfate, heparan sulfate, keratin sulfate or hyaluronic acid;
- the composition having a pH of 6.0-8.0 and an osmolality of 200-400 mOsmol/L.
2 more elements
A viscoelastic composition comprising:
- a. a buffered balanced slat solution;
- b. hydroxypropyl methyl cellulose;
- c. a glycosaminoglycan;
- and,
- d. at least one growth factor or growth supplement;
- the composition having a pH of 6.0-8.0 and an osmolality of 200-400 mOsmol/L.
3 more elements
A viscoelastic composition comprising:
- a. a buffered balanced salt solution;
- b. hydroxypropyl methyl cellulose;
- c. Epidermal Growth Factor (EGF);
- and,
- d. a glycosaminoglycan which is dermatin sulfate, heparin sulfate, heparan sulfate, keratin sulfate or hyaluronic acid;
- the composition having a pH of 6.0-8.0 and an osmolality of 200-400 mOsmol/L.
3 more elements
A viscoelastic composition comprising:
- a. a buffered balanced slat solution;
- b. hydroxyropyl methyl cellulose;
- c. a glycosaminoglycan;
- d. Epidermal Growth Factor (EGF);
- and,
- e. insulin;
- the composition having a pH of 6.0-8.0 and an osmolality of 200-400 mOsmol/L.
4 more elements
Dependencies are inferred from the claim text.