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US 5,204,266 AGranted
Method and apparatus for liquid phase calibration of oxygen and carbon dioxide partial pressure
AssigneeInstrumentation Laboratory Company
InventorClaudio Calzi
Life of this patent
Estimating the term…
Abstract
A pre-determined amount of solubilized reagent is reacted to release CO.sub.2 in a controlled-temperature reaction vessel and a controlled-pressure area adjacent the reaction vessel.
Claims11
A method of preparing a substance in the liquid phase having a pre-determined partial O.sub.2 and CO.sub.2 pressure, useful for calibrating analytical instruments of the type used to measure blood gases, which method comprises:
- a) providing a solution of reagents adapted to generate CO.sub.2,
- b) affecting in a pre-determined manner the concentration of O.sub.2 in the solution,
- c) conveying the reagent solution to a reaction vessel to conduct a reaction with a pre-determined amount of CO.sub.2 being generated, wherein the reagent solution is conveyed to the reaction vessel through a pressure equalizer exposed to the atmosphere, to equilibrate the pO.sub.2 of the reagent solution,
- d) measuring the pressure and temperature in the reaction vessel, and
- e) conveying the reacted solution from the reaction vessel to an analytical apparatus for calibration of the analytical apparatus based upon the partial O.sub.2 and CO.sub.2 pressures of the reacted solution.
2 more elements
An apparatus for preparing a solution having a predeterminted partial O.sub.2 and CO.sub.2 pressure, useful for calibrating analytical instruments of the type used for measuring blood gases, comprising:
- a. a container vessel for a reagent solution adapted to react to generate CO.sub.2,
- b. pump means for transferring an amount of reagent from the container vessel into a reaction vessel through pressure equalizing means which is exposed to the atmosphere for bringing the pO.sub.2 in the reagent solution into equilibrium with atmospheric pO.sub.2,
- c. means for measuring temperature in the reaction vessel and pressure in the area adjacent said vessel, and
- d. withdrawing means for conveying the reacted solution into the reaction vessel to the analytical instrument for calibration thereof.
1 more element
Dependencies are inferred from the claim text.