Method for validation of calibration standards in an automatic chemical analyzer
AssigneeE. I. Du Pont de Nemours and Company
InventorJon J. Kaminer
Life of this patent
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Abstract
In an automated analyzer that measures concentration of samples by comparing changes in a detector response caused by said samples to a calibration curve or factor based on one or more different calibration standards stored in the analyzer, a replacement calibration standard is validated automatically by processing a portion of said replacement calibration standard as a sample prior to accepting the new calibration standard as a valid standard.
Claims1
In a method for analyzing the concentration of a sample using an automatic analyzer wherein the possibility of human operator faults in entry of calibration standard concentrations or mislabeled standards exists that includes the steps of generating a calibration curve by means of said automated analyzer based on the concentrations of one or more calibration standards coupled to said automated analyzer and storing said curve in said analyzer, each of said calibration standards having a different known concentration, detecting a change in response caused by the concentration of said sample and comparing said change to said calibration curve to determine if said concentration of said sample is within a predetermined range of said calibration curve, the improvement being validating the concentration of a replacement calibration standard to be used in place of an expended calibration standard in said analyzer, said improvement comprising:
- using a portion of said replacement calibration standard as a sample, comparing said concentration of said portion to said calibration curve and signaling if said concentration of said portion is not within said predetermined range.
Dependencies are inferred from the claim text.