Substituted phenols
AssigneeBoehringer Mannheim GmbH
InventorsMartina Junius-Comer, Bernd Vogt, Rupert Herrmann
Life of this patent
Estimating the term…
Abstract
The present invention provides a colorimetric process for the detection of an oxidative coupling reaction in which a coupling component is reacted with a developer component in the presence of an oxidation agent to give a colored material, wherein, as coupling component, there is used a compound of the general formula: ##STR1## in which X is a bromine or chlorine atom, n is 1, 2 or 3, Y is COOR, CONRR', SO.sub.3 R, SO.sub.2 NRR', OR, NRR' or NRR'R".sym. and R, R' and R", independently of one another, are hydrogen atoms or C.sub.1 -C.sub.3 -alkyl radicals. The present invention also provides a reagent which contains the above compound, as well as new substituted phenols and a process for the preparation thereof.
Claims39
Compounds of the formula:
- ##STR9## wherein X is bromine or chlorine, n is 1, 2 or 3, Y is COOR, CONRR', SO.sub.3 R, SO.sub.2 NRR' or OR and R and R', independently of one another, are hydrogen or C.sub.1 -C.sub.3 -alkyl.
Process for the preparation of compounds of the formula:
- ##STR10## wherein X is bromine or chlorine, n is 1, 2 or 3, Y is COOR, CONRR', SO.sub.3 R, SO.sub.2 NRR' or OR and R and R', independently of one another, are hydrogen or C.sub.1 -C.sub.3 -alkyl, comprising
- reacting a compound of the formula:
- ##STR11## in which n and Y have the above-given meanings by nitration in the 6-position of the aromatic ring to give a compound of the formula:
- ##STR12## in which n and Y have the above-given meanings, subsequently reacting the compound (III) by bromination or chlorination in the 2- and 4-position of the aromatic ring to give a compound of the formula:
- ##STR13## is which n and Y have the above-given meanings and X is bromine or chlorine, and
- removing the nitro group in the 6-position of the aromatic ring to give the end product (I).
Colorimetric process for the detection of an oxidative coupling reaction in which a coupling component is reacted with a developer component in the presence of an oxidation agent to give a colored material, wherein the coupling component, is a compound of the formula:
- ##STR14## in which X is bromine or chlorine, n is 1, 2 or 3, Y is COOR, CONRR', SO.sub.3 R, SO.sub.2 NRR', OR, NRR' or NRR'R".sup.+ and R, R' and R", independently of one another, are hydrogen or C.sub.1 -C.sub.3 -alkyls.
Reagent for the detection of an oxidative coupling reaction in which a coupling component is reacted with a developer component in the presence of an oxidation agent to give a colored material, wherein the reagent contains a compound of the formula:
- ##STR15## as a coupling component wherein X is bromine or chlorine, n is 1, 2 or 3, Y is COOR, CONRR', SO.sub.3 R, SO.sub.2 NNR', OR, NNR' or NNR'R".sup.+ and R, R' and R", independently of one another, are hydrogen or C.sub.1 -C.sub.3 -alkyl, an appropriate buffer and optionally wetting agents, activators or other adjuvants.
Dependencies are inferred from the claim text.