Packing material for liquid chromatography
AssigneeShiseido Company, Ltd.
InventorsHiroshi Kutsuna, Yoshihiro Shiojima, Tsuneo Suhara, Hiroshi Fukui, Yutaka Ohtsu, Michihiro Yamaguchi
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Abstract
A packing material for liquid chromatography bears a polyalkylene polyamine moiety linked through a spacer moiety as the pendant group to a porous silica gel coated with a silicone polymer, and optionally is crosslinked by a crosslinking agent on two or more amino group of the different polyalkylene polyamine moieties, and a process for production thereof. Such a packing material is especially useful in the analysis of sugars.
Claims9
A packing material for liquid chromatography comprising a moiety derived from a porous silica gel coated with a silicone polymer containing a SiH group, a spacer moiety having two ends and a polyalkylene polyamine portion having an amino group capable of bonding to the spacer moiety, said packing material wherein:
- A. the silicon atom derived from a SiH group of the aforesaid silica gel moiety is silicon-carbon covalently bonded to one end of the spacer moiety, and the other end of the spacer moiety is carbon-nitrogen or sulfur-nitrogen covalently bonded to the amino group of the polyalkylene polyamine;
- and
- B. the spacer constituting portion between said both bonds is a group having 3 to 15 constituent atoms of a main chain, and comprises a substituted or unsubstituted hydrocarbon chain which is or is not interrupted with at least one oxygen atom, sulfur atom or nitrogen atom.
Dependencies are inferred from the claim text.