Biologically compatible collagenous reaction product and articles useful as medical implants produced therefrom
AssigneeAutogenesis Technologies, Inc.
InventorsCharles D. Kelman, Dale P. Devore
Life of this patent
Estimating the term…
Abstract
The present invention provides a biologically compatible collagenous reaction product comprising ethylenically unsaturated or polymeric substituted collagen, the monomeric substituents being essentially free of nitrogen, e.g., methacrylate, styrene, polyvinyl, ethylene. The collagenous reaction product can be polymerized, e.g., by exposure to UV irradiation, chemical agents or atmospheric oxygen, and molded to form useful medical implant articles. Methods of preparation are also provided.
Claims9
A shaped article useful for medical implantation comprising a biocompatible collagenous polymer of collagen modified with an acylating agent selected from the group consisting of glutaric anhydride, succinic anhydride, and maleic anhydride and at least one other acylating agent selected from the group consisting of methacrylic anhydride, beta-styrene sulfonyl chloride, ethylene-maleic anhydride copolymer, styrene-maleic anhydride copolymer and poly(vinyl) sulfonic acid.
A shaped article useful for medical implantation comprising a biocompatible collagenous polymer of collagen modified with an acrylating agent selected from the group consisting of methacrylic anhydride, beta-styrene sulfonyl chloride, ethylene-maleic anhydride copolymer, styrene-maleic anhydride copolymer, and poly(vinyl) sulfonic acid.
Dependencies are inferred from the claim text.