Anti-inflammatory carboxycyclic acetal pregnane derivatives

Abstract

Compounds of the formula: ##STR1## wherein X is H, F, Cl, or CH.sub.3 and Y is ##STR2## wherein R.sub.1 is H, alkyl of 1-5 carbon atoms, phenyl, or benzyl; R.sub.2 is COOR.sub.6, R.sub.5 COOR.sub.6, or R.sub.5 CONHR.sub.6 ; R.sub.3 is H, F, OH, or CH.sub.3 ; R.sub.4 is CH.sub.2 OH, CH.sub.2 OCOR.sub.6, COOR.sub.6, or CONHR.sub.6 ; R.sub.5 is alkyl of 1-3 carbon atoms; R.sub.6 is alkyl of 1-5 carbon atoms, or benzyl; represents a single or double bond; .about. represents .alpha.-position, .beta.-position, or a mixture of both .alpha.- and .beta.-positions; and -- represents .alpha.-position; and methods for preparing the same.

Dependencies are inferred from the claim text.