Digoxigenin derivatives and use thereof
AssigneeBoehringer Mannheim GmbH
InventorsErasmus Huber, Klaus Muhlegger, Herbert von der Eltz, Bruno Zink
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AssigneeBoehringer Mannheim GmbH
InventorsErasmus Huber, Klaus Muhlegger, Herbert von der Eltz, Bruno Zink
Estimating the term…
The present invention provides digoxigenin derivatives of the formula: ##STR1## wherein n is a whole number of from 1 to 4 and Z is a carboxyl group or a functional derivative derived therefrom. The present invention also provides digoxigenin conjugates of the general formula: ##STR2## wherein the carrier is an immunogenic carrier material, a nucleic acid or a labelled immunocomponent of a labelled digoxigenin immunoconjugate for use in an immunoassay, m is a number from 1 to the number of coupling positions available on the carrier and Y is the group formed by the reaction of the carboxyl function Z of the digoxigenin derivative of general formula (I) with the reacting position of the carrier material. Also described are uses of these conjugates as nucleic acid probes, immunogens, and in immunoassay.
Digoxigenin derivative of formula:
Digoxigenin conjugate of the formula:
Dependencies are inferred from the claim text.