Preparation of mixed lithium amide reagents
AssigneeCyprus Foote Mineral Company
InventorW. Novis Smith, Jr.
Life of this patent
Estimating the term…
Abstract
A method for preparing a poorly soluble lithium amides in greater concentration by preparing a mixture of lithium amides wherein one of said lithium amides is soluble and another lithium amide is less soluble, and the reagent compositions formed thereby.
Claims16
A method of preparing lithium amides in a greater concentration which comprises the step of reacting in a suitable substantially ether free hydrocarbon solvent an alkyl lithium and a mixture of amines of the formula selected from the group consisting of:
- ##STR3## wherein at least one lithium amide formed is by itself soluble in said solvent and one of said lithium amides is by itself less soluble in said solvent, and R is hydrogen, an alkyl to 1 to 8 carbon atoms, alkyl phenyl or an alkyl monocyclic aliphatic group, R' and R" are the same or different and each represent hydrogen, an alkyl of 1 to 8 carbon atoms, an alkyl phenyl, an alkyl monocyclic aliphatic group, R" is hydrogen, alkyl or alkoxy, R.sup.4 is hydrogen, alkyl or phenyl,
- W is from 0 to 4,
- x is an integer of 2 to 8, and
- y is an integer of 2 to 6,
- with the proviso that at least one of R', R", and R"' is hydrogen.
A process of preparing a solution of lithium amides of at least 0.1 molar solution comprising reacting an alkyl lithium with a mixture of diisopropylamine and diisobutylamine in a suitable ether free solvent.
A process for preparing a solution of lithium amides of at least 0.1 molar solution comprising reacting in a suitable substantially ether free hydrocarbon solvent an alkyl lithium with mixtures of a monoamine of the formula:
- ##STR4## wherein R, and R" each represent hydrogen, an alkyl group of 1 to 8 carbon atoms, alkyl phenyl or an alkyl monocyclic aliphatic group, and a diamine of the formula:
- ##STR5## wherein R,R' and R" are as hereinbefore described and x is an integer of 2 to 8, whereby at least one lithium amide formed is by itself soluble in said solvent and one of said lithium amides is by itself less soluble in said solvent.
Dependencies are inferred from the claim text.