Antibiotics unphenelfamycin and phenelfamycins A-D
AssigneeAbbott Laboratories
InventorsJill E. Hochlowski, Mark H. Buytendorp, Randal H. Chen, James B. McAlpine, Robert J. Theriault, Marianna Jackson, James P. Karwowski
Life of this patent
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Abstract
New antibiotics, unphenelfamycin and phenelfamycins A-D, are produced by microorganisms belonging to the genus Streptomyces. The antibiotics have antibacterial activity against gram-positive and gram-negative anaerobic organisms and are effective in improving the feed efficiency and growth rate of livestock, including poultry.
Claims12
A compound of the formula:
- ##STR2## or a pharmaceutically acceptable salt thereof, wherein R.sub.1 and R.sub.2 are independently selected from the group consisting of hydrogen and --C(O)CH.sub.2 C.sub.6 H.sub.5, with the proviso that at least one of R.sub.2 and R.sub.2 is hydrogen, and R.sub.3 is selected from the group consisting of hydrogen and ##STR3##
A composition having antibacterial activity which comprises a pharmaceutically acceptable carrier and a therapeutically effective amount of a compound of the formula:
- ##STR4## or a pharmaceutically acceptable salt thereof.
A composition having antibacterial activity which comprises a pharmaceutically acceptable carrier and a therapeutically effective amount of a compound of the formula:
- ##STR5## or a pharmaceutically acceptable salt thereof.
A composition having antibacterial activity which comprises a pharmaceutically acceptable carrier and a therapeutically effective amount of a compound of the formula:
- ##STR6## or a pharmaceutically acceptable salt thereof.
A composition having antibacterial activity which comprises a pharmaceutically acceptable carrier and a therapeutically effective amount of a compound of the formula:
- ##STR7## or a pharmaceutically acceptable salt thereof.
A composition having antibacterial activity which comprises a pharmaceutically acceptable carrier and a therapeutically effective amount of a compound of the formula:
- ##STR8## or a pharmaceutically acceptable salt thereof.
Dependencies are inferred from the claim text.