Back to results
US 5,190,775 AGranted
Encapsulated bioactive substances
AssigneeBalchem Corporation
InventorRobert E. Klose
Life of this patent
Estimating the term…
Loading patent…
Loading patent…
AssigneeBalchem Corporation
InventorRobert E. Klose
Estimating the term…
A composition of matter and method for administering a bioactive substance to the post-rumen portion of the digestive system of a ruminant substantially without introducing the substance to the rumen portion of the digestive system is provided. The composition of matter comprises particles which have a specific gravity between about 0.3 and 2.0, preferably between about 1.0 and 2.0. The particles comprises a core comprising bioactive substance; a hydrophobic coating essentially completely encapsulating said core in a quantity sufficient to essentially preclude introduction of bioactive substance into the rumen; and a surfactant applied to the surface of the hydrophobic coating in a quantity sufficient to ensure that said particles do not float on the rumen. The method comprises orally administering this composition of matter to a ruminant.
A method for administering a bioactive substance to the post-rumen portion of the digestive system of a ruminant substantially without introducing the substance to the rumen portion of the digestive system, said method comprising orally administering a composition of matter containing particles having a specific gravity between about 0.3 and 2.0 and said particles consisting essentially of:
A method according to claim 11, wherein the surfactant is selected from the group consisting of polysorbate 60, polysorbate 80, propylene glycol, sodium dioctylsulfosuccinate, sodium lauryl sulfate, lactylic esters of fatty acids, polyglycerol esters of fatty acids, and mixtures thereof.
Dependencies are inferred from the claim text.