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US 5,188,967 AGranted
Agents for the in vitro diagnosis of malignant cells originating in the digestive tract
AssigneesInstitut Pasteur, Centre National De La Recherche Scientifique, Institut National de la Sante et de la Recherche Medicale
InventorsDaniel Louvard, Brigitte Dudouet, Sylvie Robine, Monique Arpin, Eric Pringault, Alphonse Garcia
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Abstract
In vitro diagnosis of malignant cells originating in the digestive tract by placing a biological specimen in contact with a reagent recognizing the gene coding for human villin.
Claims6
An in vitro method of detecting a tumor associated with cells of renal or intestinal origin, wherein said method comprises
- (a) contacting a specimen of tissue or serum from a human subject with a reagent comprising detectable anti-villin antibodies, to form villin- anti-villin immune complexes;
- (b) detecting the presence of said immune complexes;
- and
- (c) on the basis of the presence of said immune complexes, diagnosing the presence or absence of said tumor.
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Dependencies are inferred from the claim text.