Method of preparing autologous plasma fibrin and application apparatus therefor
AssigneeThe Research Foundation of State University of New York
InventorDennis K. Galanakis
Life of this patent
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Abstract
A method of preparing autologous plasma fibrin perioperatively to induce local hemostasis is disclosed. The autologous plasma fibrin is thereafter simultaneously expelled onto a treatment site along with a physiologically acceptable thrombin solution to effect hemostasis at the site. An apparatus for simultaneously expelling the contents of vessels which separately contain the autologous plasma fibrin and thrombin solutions, respectively, is also disclosed. A kit for obtaining a sample of blood, extracting plasma fibrin therefrom, as well as all necessary syringes, needles, reagents, and the inventive apparatus is also disclosed.
Claims25
A method of treating with autologous mammalian plasma fibrin to affect hemostasis, comprising the steps of:
- (a) obtaining a sample of blood from said mammal;
- (b) substantially immediately separating the whole plasma from said blood obtained in step (a);
- and
- (c) contacting said whole plasma resulting from step (b) with thrombin in a physiologically acceptable solution at a rate and in a volume at the site of treatment to provide fibrin coagulation at said site.
A kit for treatment with autologous mammalian plasma fibrin to effect hemostasis, comprising:
- (a) means for obtaining a sample of blood from said mammal, said means including structure for effecting plasma separation of said blood, said structure having at least two open ends located opposite each other;
- (b) means for extracting whole plasma from said obtaining means, said plasma extracting means including structure having at least two open ends located opposite each other;
- (c) means for providing a physiologically acceptable thrombin solution, said means including structure having at least two open ends distally located, said plasma extracting means and said means for providing a physiologically acceptable thrombin solution having substantially equal cross-sectional area;
- (d) means for simultaneously expelling said whole plasma from said extracting means and said thrombin solution from said means for providing locally at the site of treatment.
Dependencies are inferred from the claim text.