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US 5,183,896 AGranted
Derivatives of 1,2,5,6-tetrahydropyridin-3-carboxaldehyde oxime
AssigneeRoussel Uclaf
InventorsEmilio Toja, Carla Bonetti, Fernando Barzaghi, Giulio Galliani
Life of this patent
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Abstract
Compounds of the formula ##STR1## which have a long-lasting cholinomimetic activity by oral route. Also disclosed are methods for preparing the compounds and pharmaceutical compositions containing the compounds.
Claims11
A compound of formula I ##STR8## in which:
- R represents hydrogen, a linear, branched or cyclic alkyl, alkenyl or alkynyl containing up to 8 carbon atoms, and R' and R" are identical or different from each other, and represent a hydrogen, a linear, branched or cyclic alkyl, alkenyl or alkynyl containing up to 8 carbon atoms, or form together with the nitrogen to which they are linked a heterocyclic radical selected from the group consisting of piperidinyl, piperazinyl, N-methyl piperazinyl and morpholinyl, said morpholinyl being optionally substituted by an alkyl radical containing up to 4 carbon atoms.
The compound (di(2-propenyl)-aminocarbonyl)-methyl 3-(methoxyiminomethyl)-1,2, 5,6-tetrahydropyridine-1-carboxylate.
Dependencies are inferred from the claim text.