Conjugate of adriamycin and cyclodextrin

Abstract

Adriamycin derivatives represented by formula (I) ##STR1## wherein R denotes a divalent hydrocarbon group, CD denotes a cyclodextrin residue, m is 1 to 8, and n is 0 to 8. The compounds exhibit excellent anti-cancer activity over a wide administration range, have low toxicity and sustained release, and maintain activity for a long period of time; thus, they are quite useful as an anti-cancer agent.

Dependencies are inferred from the claim text.