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US 5,183,758 AGranted
Production of 7-chloro-3-methoxy-2'-N-methyltetracycline with Actinomadura brunnea
AssigneeSchering Corporation
InventorAnn C. Horan
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Abstract
An antibiotic complex is produced by the microorganism, Actinomadura brunnea NRRL 15216, ATCC 39216. A novel antibiotic 7-chloro-8-methoxy-2'-N-methyltetracycline, isolated from the antibiotic complex, is active against gram-positive and gram-negative aerobes.
Claims1
A biologically pure culture of the microorganism Actinomadura brunnea ATCC 39216, said culture being capable of producing 7-chloro-8-methoxy-2'-N-methyltetracycline in a recoverable quantity upon fermentation, under aerobic conditions in an aqueous medium containing assimilable sources of nitrogen and carbon.
Dependencies are inferred from the claim text.