Pressing not delayed release of active compound, process for its production and use of polyhydroxybutyric acid for the production of such a pressing
AssigneePCD Polymere Gesellschaft m.b.H.
InventorsBrigitta Korsatko-Wabnegg, Werner Korsatko
Life of this patent
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Abstract
Pressing containing homo- and/or copolymers of D(-)-3-hydroxybutyric acid, at least one solid disintegrant and at least one solid pharmaceutical active compound, process for its production and the use of homo- and/or copolymers of D(-)-3-hydroxybutyric acid for the production of such a pressing.
Claims6
Pressing for oral administration having non-delayed release of active compound comprising at least one solid pharmaceutically active compound and as matrix material a homo- and/or copolymer of D(-)-3-hydroxybutyric acid and an amount of at least one solid disintegrant sufficient to cancel the delayed release properties of the homo- and/or copolymer of D(-)-3-hydroxybutyric acid.
A process for the production of a pressing having non-delayed release of a pharmaceutically active compound, which comprises thoroughly mixing a homo- and/or copolymer of D(-)-3-hydroxybutyric acid with an amount of at least one solid disintegrant sufficient to cancel the delayed release properties of the homo- and/or copolymer of D(-)-3-hydroxybutyric acid, and at least one solid pharmaceutically active compound to form a mixture and compressing the mixture with or without pregranulation.
Dependencies are inferred from the claim text.