Automatic immunity analysis apparatus with magnetic particle separation
AssigneesKabushiki Kaisha Nittec, Mitsui Pharmaceuticals, Inc.
InventorKoichi Wakatake
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AssigneesKabushiki Kaisha Nittec, Mitsui Pharmaceuticals, Inc.
InventorKoichi Wakatake
Estimating the term…
An immunity analysis apparatus for use with magnetic particles in which a sample is transferred to a reaction vessel and the reaction vessel is conveyed past several devices for adding and agitating a magnetic particle solution, adding a stroma solution, absorbing the particles to an inner wall of the reaction vessels to remove the reaction solution, adding an enzyme labelling antibody solution, absorbing the particle on an inner wall a second time to remove the resulting solution, adding a stop solution, measuring the result, and cleaning the reaction vessels for a reuse. The device additionally has structure for agitating the magnetic particle reagent solution containers and moving a pipet arm independent of an L-shaped agitating rod arm during a portion of its movement to supply the reaction vessels with the magnetic particle solution.
An automatic immunity analysis apparatus comprising reaction vessels arranged in a series, a conveying means for said reaction vessels, a first dividing means for sucking a sample in a predetermined quantity at a predetermined position and dividing and charging said sample into each of said reaction vessels, a first agitating means for dividing, charging and agitating an antibody insoluble magnetic solution into each of said reaction vessels containing said sample divided and charged, a second dividing means which is positioned after said first agitating means, said second dividing means for dividing and charging a stroma solution into each of said vessels, a first adsorbing means for adsorbing said antibody insoluble magnetic solution onto an inner wall surface of each of said reaction vessels, a first cleaning means for discarding a reactions solution out of each of said reaction vessels while said antibody insoluble magnetic solution is still adsorbed on the inner wall of each of said reaction vessels and then cleaning each of said vessels, a second agitating means for dividing and agitating an enzyme labeling antibody solution, a second absorbing means for adsorbing said antibody insoluble magnetic solution onto an inner wall surface of each of said reaction vessels, a second cleaning means for discarding a reaction solution out of each of said reaction vessels while said antibody insoluble magnetic solution is still adsorbed on the inner wall of each of said reaction vessels and then cleaning each of said vessels, a third dividing means for dividing and charging a reaction stop solution, a measuring means for optically measuring a sample in each of said reaction vessels at an optical measuring position, and a third cleaning means for cleaning the inside of each of said reaction vessels after completion of a measurement, wherein said first dividing means, said first agitating means, said second dividing means, said first adsorbing means, said first cleaning means, said second agitating means, said second absorbing means, said second cleaning means, said third dividing means, said measuring means and said third cleaning means are arranged sequentially beginning with said first dividing means and ending with said third cleaning means on said conveying means in said automatic immunity analysis apparatus, wherein
An automatic immunity analysis apparatus comprising reaction vessels arranged in a series, a conveying means for said reaction vessels, a first dividing means for sucking a sample in a predetermined quantity at a predetermined position and dividing and charging said sample into each of said reaction vessels, a first agitating means for dividing, charging and agitating an antibody insoluble magnetic solution into each of said reaction vessels containing said sample divided and charged, a second dividing means which is positioned after said first agitating means, said second dividing means for dividing and charging a stroma solution into each of said vessels, a first adsorbing means for adsorbing said antibody insoluble magnetic solution onto an inner wall surface of each of said reaction vessels, a first cleaning means for discarding a reaction solution out of each of said reaction vessels while said antibody insoluble magnetic solution is still adsorbed on the inner wall of each of said reaction vessels and then cleaning each of said vessels, a second agitating means for dividing and agitating an enzyme labeling antibody solution, a second adsorbing means for adsorbing said antibody insoluble magnetic solution onto an inner wall surface of each of said reaction vessels, a second cleaning means for discarding a reaction solution out of each of said reaction vessels while said antibody insoluble magnetic solution is still adsorbed on the inner wall of each of said reaction vessels and then cleaning each of said vessels, a third dividing means for dividing and charging a reaction stop solution, a measuring means for optically measuring a sample in each of said reaction vessels at an optical measuring position, and a third cleaning means for cleaning the inside of each of said reaction vessels after completion of a measurement, wherein said first dividing means, said first agitating means, said second dividing means, said first adsorbing means, said first cleaning means, said second agitating means, said second absorbing means said second cleaning means, said third dividing means, said measuring means and said third cleaning means are arranged sequentially beginning with said first dividing means and ending with said third cleaning means on said conveying means in said automatic immunity analysis apparatus, wherein said first agitating means further comprises an agitating rod arm having a substantially L-shaped configuration and a pipet arm, where said agitating rod arm is equipped with an agitating body at an intermediate portion and a draining pipet supported by a draining pipet body, said draining pipet body supported on a bearing at a top and end portion of said agitating rod arm, and said pipet arm is equipped with a dividing pipet at an end portion, wherein said agitating rod arm and said pipet arm are supported by a shaft, said shaft rotatably supporting said agitating rod arm and bearingly supporting said pipet arm and means for rotating said pipet arm independently of said agitating arm and for pushing said draining pipet body out of place;
Dependencies are inferred from the claim text.