1-hydroxyvitamin D derivatives
AssigneeNisshin Flour Milling Co., Ltd.
InventorYoji Tachibana
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Abstract
1-Hydroxyvitamin D derivatives which are esters of 1-hydroxyvitamin D with vitamin A acid. They are useful for an agent for preventing and treating osteoporosis, cutaneous ulcer and tumor.
Claims7
A 1-hydroxyvitamin D derivative having the formula (I) ##STR17## wherein A represents an acyl residue derived from vitamin A acid, X means a hydroxyl group and R represents a group of the formula (II) ##STR18## wherein R.sub.1 and R.sub.2 each represent hydrogen atoms or together form a carbon-carbon double bond, R.sub.3 represents a hydrogen atom, a C.sub.1 -C.sub.4 alkyl group or a hydroxyl group and R.sub.4 represents a hydrogen atom or a hydroxyl group.
Dependencies are inferred from the claim text.