Method for bonding an analyte-sensitive dye compound to an addition-cure silicone
AssigneePuritan-Bennett Corporation
InventorsHenry K. Hui, George A. Divers, III, Carmen Soikowski
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Abstract
A method for covalently bonding an analyte sensitive dye compound to an addition-cure silicone is disclosed. The method includes a first step of functionalizing the dye compound to provide a linker arm with an isolated multiple bond. A second step include hydrosilylating the functionalized dye with polymethylhydrosiloxane. The resulting compound is cross-linked with vinyl-terminated polysiloxane in a third and final step.
Claims2
A method for bonding an analyte-sensitive indicator substance selected from the group consisting of perylene, benzoperylene, coronene, and decacyclene to addition-cure silicone to form a sensor element, comprising the steps of:
- adding butyllithium and tetramethylethylenediamine to the indicator substance in a tetrahydrofuran/hexamethylphosphoramide solvent system to generate a mixture containing the carbanion of the indicator substance;
- adding 8-bromo-1-octene to the indicator substance carbanion mixture to form a functionalized indicator substance;
- reacting the functionalized indicator substance with polymethylhydrosiloxane to form an indicator-bound silicone liquid;
- and
- cross-linking the indicator-bound silicone liquid with vinyl-terminated polysiloxane to form said sensor element.
Dependencies are inferred from the claim text.