Process for producing carriers for immunoassay

A process for producing carriers for an immunoassay, comprising the steps of:

• 1) cutting a polystyrene material into pellets,
• 2) polymerizing the polystyrene pellets and a monomer required for forming polystyrene in the presence of a polymerization initiator and a crosslinking agent in a medium in which the pellets and the monomer are hardly soluble, to obtain spherical polystyrene beads, and
• 3) roughening the surface of the spherical polystyrene beads by stirring the spherical polystyrene beads together with aluminum oxide in a medium in which the polystyrene beads and the aluminum oxide are insoluble.

A process for producing carriers for an immunoassay, comprising the steps of:

• 1) cutting a polystyrene material into pellets,
• 2) polymerizing the polystyrene pellets and a monomer required for forming polystyrene in the presence of a polymerization initiator and a crosslinking agent in a medium in which the pellets and the monomer are hardly soluble, to obtain spherical polystyrene beads, and
• 3) roughening the surface of the spherical polystyrene beads, wherein the polymerization step is conducted in the presence of an additive inert to the polymerization reaction to obtain spherical polystyrene beads having the additive contained in their surface, and the surface roughening step is conducted by treating the surface of the spherical polystyrene beads with an extracting medium or subjecting the surface to evaporation treatment.

A process for producing carriers for an immunoassay, comprising the steps of:

• 1) cutting a polystyrene material into pellets,
• 2) polymerizing the polystyrene pellets and a monomer required for forming polystyrene in the presence of a polymerization initiator and a crosslinking agent in a polyvinyl alcohol solution, to obtain spherical polystyrene beads, and
• 3) roughening the surface of the spherical polystyrene beads.