Inhibitors of lysyl oxidase

A method of treating diseases and conditions associated with the abnormal deposition of collagen in a patient in need thereof which comprises administering to the patient a therapeutically effective amount for treating said disease of a compound of the formula ##STR3## wherein X and Y are identical and are each either a fluoro, chloro, or bromo group or one of X and Y is a hydrogen and the other is a fluoro, chloro, or bromo group;

• R.sub.1 is a hydrogen or a (C.sub.1 -C.sub.4)alkyl group;
• A is a divalent radical group selected from ##STR4## wherein R.sub.2 is hydrogen, methyl, or ethyl, and m and n, independently, are an integer from 0 to 16, provided that m+n cannot be greater than 17;
• --(CH.sub.2).sub.p --D--(CH.sub.2).sub.q --
• wherein
• D is oxygen or sulfur, p is an integer of from 0 to 16, and q is an integer of from 1 to 16, provided that m+n cannot be greater than 17;
• and
• --(CH.sub.2).sub.r --CH.dbd.CH--(CH.sub.2).sub.s --
• wherein
• s is an integer of from 1 to 16 and r is an integer of from 0 to 16, provided that r+s cannot be greater than 16;
• and
• R is 2- or 3-thienyl
• or a pharmaceutically acceptable salt thereof.