Clamping and tensioning device for clamping a printing plate on a cylinder of a printing machine, comprising a tensioning bar and a clamping bar having substantially radially extending, mutually opposing clamping surfaces for gripping therebetween a bent end of a printing plate, said tensioning bar being formed as a pivotal double lever, tension spring means engageable with said tensioning bar for applying a tensioning force thereto in a tensioning direction, adjusting means engageable with said tensioning bar and actuatable for pivoting said tensioning bar against the tensioning force applied by said tension spring means, said clamping bar being formed as a pivotal double lever connected to said tensioning bar, clamping spring means engaging with said clamping bar for pressing said clamping surface of said clamping bar against the corresponding clamping surface of said tensioning bar with a clamping force for holding a printing plate therebetween, said clamping bar being further formed with a holding element, a fixed stop cooperatively engageable by said holding element for pivoting said clamping bar against the force of said clamping spring means when said adjusting means are actuated.