US 5,180,832 AGranted

(3-pyridinyl)methanone oxime derivatives

AssigneeJanssen Pharmaceutica NV

InventorsEddy J. E. Freyne, Alfons H. M. Raeymaekers, Victor Sipido, Marc G. Venet

Life of this patent

Estimating the term…

Abstract

Novel [[[(3-pyridinyl)methylen]amino]oxy]alkanoic acids and esters, compositions containing the same, and methods of treating clinical conditions related with the production of thromboxane A.sub.2, prostacyclin and/or prostaglandin s D.sub.2, E.sub.3 and F.sub.2.alpha..

Claims9

Dependent claims

A compound of the formula:

##STR13## an N-oxide form, an alkali or alkaline earth metal substitution salt, or a stereochemically isomeric form thereof, wherein:
R represents phenyl or naphthalenyl wherein said phenyl and naphthalenyl are each optionally substituted with up to 2 substituents being each independently selected from the group consisting of C.sub.1-6 alkyloxy, di(C.sub.1-6 alkyloxy)methyl, formyl, and trifluoromethyl provided that R represents other than unsubstituted phenyl.

Dependencies are inferred from the claim text.

Facts

Application: 07/583,758Filed 17 Sep 1990 · division
Priority: 4 Nov 1985
Granted: 19 Jan 1993
Term ends: Not estimatedThe source records don’t support an estimate.

Classification6 codes

C07D 213/53
Radicals substituted by doubly-bound oxygen, sulfur, or nitrogen atoms, or by two such atoms singly-bound to the same carbon atom: nitrogen atoms
C07D 213/89
Having three double bonds between ring members or between ring members and non-ring members: with hetero atoms directly attached to the ring…
C07D 401/06
Containing two hetero rings: linked by a carbon chain containing only aliphatic carbon atoms
C07D 405/06
Containing two hetero rings: linked by a carbon chain containing only aliphatic carbon atoms

Family

Serial794,999Parent of this continuation-in-part · filed 4 Nov 1985
Serial888,670Parent of this continuation · filed 23 Jul 1986
Serial156,513Parent of this continuation · filed 16 Feb 1988
Serial356,592Parent of this division · filed 23 May 1989
US 4,963,573 AParent of this division
US 4,746,671 AParent of this continuation
US 5,180,832 AThis patent

From the US filing history. Foreign family members aren’t listed.

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Abstract

Facts

Application

07/583,758Filed 17 Sep 1990 · division

Priority

4 Nov 1985

Granted

19 Jan 1993

Term ends

Not estimatedThe source records don’t support an estimate.

Classification6 codes

C07D 213/53
Radicals substituted by doubly-bound oxygen, sulfur, or nitrogen atoms, or by two such atoms singly-bound to the same carbon atom: nitrogen atoms
C07D 213/89
Having three double bonds between ring members or between ring members and non-ring members: with hetero atoms directly attached to the ring…
C07D 401/06
Containing two hetero rings: linked by a carbon chain containing only aliphatic carbon atoms
C07D 405/06
Containing two hetero rings: linked by a carbon chain containing only aliphatic carbon atoms

Family

Serial794,999Parent of this continuation-in-part · filed 4 Nov 1985

Serial888,670Parent of this continuation · filed 23 Jul 1986

Serial156,513Parent of this continuation · filed 16 Feb 1988

Serial356,592Parent of this division · filed 23 May 1989

US 4,963,573 AParent of this division

US 4,746,671 AParent of this continuation

US 5,180,832 AThis patent

From the US filing history. Foreign family members aren’t listed.