Early envelope glycoprotein of human cytomegalovirus (HMCV) and monoclonal antibodies to the glycoproteins

An isolated and purified, immunogenic, early envelope glycoprotein of human cytomegalovirus free of any other human cytomegalovirus proteins, wherein said glycoprotein has a molecular weight of about 48,000 daltons and is encoded by an early structural gene of human cytomegalovirus, which gene maps between about 0.054 and 0.064 map units of the human cytomegalovirus genome and comprises a major open reading frame having an initiation codon located 233 base pairs downstream from the major early transcription start site of the gene.