Use of sigma receptor antagonists for treatment of cocaine abuse
AssigneeThe Du Pont Merck Pharmaceutical Company
InventorLeonard Cook
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Abstract
The invention relates to a method of treating cocaine abuse or addiction in a mammal which comprises administering to the mammal an effective amount of a sigma receptor antagonist lacking or having relatively weak dopamine receptor-blocking activity, to reduce the pharmacological effects of the cocaine.
Claims33
A method of treating cocaine abuse or addiction by attenuating the pharmacological effects of cocaine in a mammal which comprises administering to the mammal :n need of such treatment an effective amount of a sigma receptor antagonist lacking or having relatively weak dopamine receptor-blocking activity, to reduce the pharmacological effects of the cocaine.
Dependencies are inferred from the claim text.