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US 5,180,667 AGranted
Genes encoding eglin C mutants
AssigneesCiba-Geigy Corporation, UCP Gen-Pharma AG
InventorsMarkus G. Grutter, Dirk Heinz, Manfred Liersch
Life of this patent
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Abstract
DNA encoding novel eglin mutants that differ from the natural eglins B and C by the replacement of amino acids in the region of the active center (amino acid 45) by other amino acids are provided. The mutants, which are produced by recombinant genetic engineering, have valuable pharmacological properties.
Claims4
An isolated and purified DNA molecule consisting essentially of a gene encoding (Arg45)-eglin C.
Dependencies are inferred from the claim text.