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US 5,180,590 AGranted
Process for the preparation of anti-inflammatory pharmaceutical agents with an ibuprofen base, with elimination, in solution, of the bitter taste, burning of the throat and intestinal toxicity
AssigneeAesculapius-Pharma S.A.
InventorsMario Carcano, Massimo Costa
Life of this patent
Estimating the term…
Abstract
Anti-inflammatory pharmaceutical compositions with an ibuprofen base which eliminate the bitter taste, the burning in the throat and the topical toxicity at the level of the intestinal wall when their effervescent aqueous solutions are taken. The proportions among the main ingredients of each dose are the following: ibuprofen, 200 to 800 mg or ibuprofen sodium salt, 221.3 to 885.2 mg; sodium bicarbonate, 2.100 to 8.402 g; and citric acid, 0.450 to 1.800 g.
Claims6
An anti-inflammatory pharmaceutical composition, consisting essentially of the following ingredients in intimate admixture:
- 200 to 800 mg ibuprofen or 221.3 to 885.2 mg ibuprofen sodium salt, 2.100 to 8.402 g sodium bicarbonate, and 0.450 to 1.800 g citric acid.
Dependencies are inferred from the claim text.