Apparatus for the preparation of samples, especially for analytical purposes
AssigneeCiba-Geigy Corporation
InventorAndreas Manz
Life of this patent
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AssigneeCiba-Geigy Corporation
InventorAndreas Manz
Estimating the term…
An apparatus (1) is used for the preparation or extraction of samples, especially for analytical purposes, from a liquid or using a carrier liquid, where only very little liquid and substrate is available or is to be used and where the sample separation is to be carried out very quickly. For this, the apparatus (1) comprises, etched or machined into a plate-shaped body (8), an essentially planar flow bed (10) which has inlets and outlets arranged at opposing ends in the direction of flow, and is covered and sealed on the processing side of the plate-shaped body (8) by a further plate, so that the flow bed (10), which has an approximately groove-shaped flat cross-section, is sealed on all sides. There extend parallel to the flow bed (10), but also machined or etched into the plate-shaped body (8), electrode chambers (13), which are connected by way of electrodes (13b) to a current source (13a) in order to generate an electric field in the flow bed (10) transversely to the direction of flow. The electrode chambers (13) are connected to the flow bed (10) by way of very fine channels (14) extending transversely to the direction of flow which permit voltage transmission but practically no transport of material, that is to say act in a similar manner to membranes. Etching technology permits a miniaturized construction of the apparatus (1).
An apparatus (1) for the preparation or extraction of samples, for analytical purposes from a liquid and/or using a carrier liquid, wherein the apparatus (1) comprises, etched or machined into an approximately plate-shaped body (8), an essentially planar flow bed (10) having at least one inlet (5,6) and one outlet (11,12), which are arranged at opposing ends in the direction of flow, and having a cover covering the margins of the flow bed (10) and the bed itself, wherein recesses that serve as electrode chambers (13) and are connected to a current source (13a) are etched or machined into the plate-shaped body (8) at both sides of and parallel to the flow bed (10), and wherein there are provided between the flow bed (10) and the electrode chambers (13) fine channels (14) which are etched or machined into plate-shaped body (8), the fine channels (14) are arranged adjacent to one another and extend transversely to the direction of flow and to the direction in which the flow bed (10) extends.
An apparatus according to claim to 3, wherein the inlet and the outlet may each comprise channels (15) from approximately 1 micrometer to approximately 100 micrometers wide and/or deep.
Dependencies are inferred from the claim text.