Substituted 3-aminosydnone imines
AssigneeCassella Aktiengellschaft
InventorsEckard Kujath, Christian Baumgartner, Karl Schonafinger, Rudi Beyerle, Melitta Just, Helmut Bohn, Jorg Ostrowski
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Abstract
Substituted 3-aminosydnone imines of the formula I ##STR1## and their pharmacologically acceptable acid addition salts, in which R.sup.1 denotes e.g. hydrogen; R.sup.2 denotes e.g. an alkyl radical; at least two of the radicals R.sup.3, R.sup.4, R.sup.5 and R.sup.6 denote alkyl radicals and the others denote hydrogen, are prepared by cyclization of a compound of the formula II ##STR2## and, if appropriate, subsequent acylation, and have useful pharmacological properties.
Claims9
4-Benzyl-3-(2,6-dimethylpiperidino)sydnone imine and its pharmacologically acceptable acid addition salts.
3-(2,6-Dimethylpiperidino)-4-(2-phenethyl)sydnone imine and its pharmacologically acceptable acid addition salts.
4-Benzyl-3-(2,6-dimethylpiperidino)sydnone imine hydrochloride.
3-(2,6-Dimethylpiperidino)-4-(2-phenethyl)sydnone imine hydrochloride.
3-(2,6-Dimethylpiperidino)-4-hexylsydnone imine and its pharmacologically acceptable acid addition salts.
3-(2,6-Dimethylpiperidino)-4-hexylsydnone imine hydrochloride.
N-Benzoyl-3-(2,6-dimethylpiperidino)-4-hexylsydnone imine.
4-Benzyl-3-(2,6-dimethylpiperidino)-N-ethoxycarbonylsydnone imine.
N-Benzoyl-3-(2,6-dimethylpiperidino)-4-(2-phenethyl)sydnone imine.
Dependencies are inferred from the claim text.