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US 5,179,000 AGranted
Method for assaying basic fetoprotein in urine and assay kit therefor
AssigneeNippon Kayaku Kabushiki Kaisha
InventorsMasaru Ishii, Yuko Seino
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Abstract
The present invention provides a method for assaying basic fetoprotein in urine comprising an antigen-antibody reaction with the use of anti-basic fetoprotein antibodies, and an assay kit used for performing said method comprising a first anti-basic fetoprotein antibody, a marker second anti-basic fetoprotein antibody, a solid phase and a standard basic fetoprotein antigen, characterized in that the first antibody and the second antibody react with antigenic determinants different from each other.
Claims5
A method for detecting the presence of urogenital cancer in an individual, wherein the method comprises:
- contacting a urine sample from the individual with at least one antibody which specifically binds basic fetoprotein,
- detecting formation of an immune complex between the antibody and basic fetoprotein and determining the amount of basic fetoprotein in the urine sample,
- wherein an elevated level of basic fetoprotein is associated with the presence of urogenital cancer.
Dependencies are inferred from the claim text.