Intermittent release dosage form
AssigneeSmithKline Beechman Corporation
InventorsLilian Kwan, William Steber
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Abstract
Veterinary delayed release dosage forms which remain in the rumeno-reticular sac of an animal over an extended period of time and in which the therapeutically active substance has a predictable and delayed release pattern. The compositions comprise a dense filler, a disintegrant and a therapeutically active substance. The dosage form has a hydrophobic polymer or co-polymer coating and can deliver a plurality of doses of a medicament intermittently at a preset time interval in the rumen.
Claims7
A delayed release dosage form for ruminants capable of delivering a dose of a medicament to the rumen which comprises a single bolus containing a medicament dispersed in a filler and a second weighted layer containing a dense filler matrix which permits the bolus to lodge in the rumen, said bolus having a hydrophobic polymeric coating.
Dependencies are inferred from the claim text.