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AssigneesTaisho Pharmaceutical Co., Ltd., Tosoh Corporation
InventorsYumiko Asami, Katsuo Komiya, Hiroo Sasaki, Hironaka Aihara
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A method for lowering serum total cholesterol in an animal by administering to the aminal an anion-exchange resin having the monomer units respectively represented by the below-given structural formulas (I), (II), (III) and (IV) in a content of 60-95 molar % of the monomer unit (I), 0-25 molar % of the monomer unit (II), 0--30 molar % of the monomer unit (III) and 1-6 molar % of themonomer unit (IV). ##STR1## wherein R.sup.1, R.sup.2 and R.sup.3 which may be the same or different respectively are hydrogen atom, a lower alkyl group or benzyl group, R.sup.4 is hydrogen atom, a lower alkyl group or hydroxy-methyl group and X is a halogen atom. The above-mentioned agents specifically bind with bile acid in the intestinal tract even in the presence of other acids.
A method for lowering serum total cholesterol in an animal comprising administering to said animal, in an amount effective for said lowering, a cholesterol-lowering agent comprising an anion-exchange resin composed of the monomer units respectively represented by the below-given structural formulas (I), (II), (III) and (IV) in a content of 60-95 molar % of the monomer unit (I), 0-25 molar % of the monomer unit (II), 0-30 molar % of the monomer unit (III) and 1-6 molar % of the monomer unit (IV) ##STR3## wherein R.sup.1, R.sup.2 and R.sup.3 which may be the same or different respectively are hydrogen atom, a lower alkyl group or benzyl group, R.sup.4 is hydrogen atom, a lower alkyl group or hydroxy-methyl group and X is a halogen atom.
Dependencies are inferred from the claim text.