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AssigneeL'oreal
InventorsSerge Forestier, Alain Lagrange, Gerard Lang, Andre Deflandre, Bernadette Luppi
Estimating the term…
The invention relates to cosmetic and pharmaceutical compositions containing the derivatives of benzylidenecamphor of formula: ##STR1## where R.sub.1 denotes H, OH, C.sub.1 -C.sub.3 alkyl or C.sub.1 -C.sub.8 alkoxy, R.sub.3 denotes OH, C.sub.1 -C.sub.3 alkyl or C.sub.1 -C.sub.8 alkoxy, or else when R.sub.1 denotes H or OH, R.sub.3 can represent C.sub.1 -C.sub.8 alkyl, R.sub.2 and R.sub.4 denote H or OH, at least one of the radicals R.sub.2 and R.sub.4 representing OH. The compounds (I) are wide-band sunscreens and antioxidants, and are utilized in the treatment of cutaneous inflammations and allergies.
A derivative of benzylidenecamphor that has formula (I'):
In a process for treating a subject afflicted with a cutaneous inflammation or an allergy by administering to the subject an effective amount of a pharmaceutically-active ingredient, the improvement wherein the active ingredient is a derivative of benzylidenecamphor that has formula (I):
A pharmaceutical composition, comprising an effective concentration of at least one benzylidenecamphor derivative in a pharmaceutically acceptable nontoxic vehicle or excipient, wherein said concentration is effective for the treatment of cutaneous inflammations and allergies and the derivative is a compound of formula (I):
A benzylidenecamphor derivative that is a member selected from the group consisting of 3'-tert-butyl-4'-hydroxy-3-benzylidene camphor, 3'5'-dimethyl-4'-hydroxy -3-benzylidene camphor, 3'5'-diisopropyl-4'-hydroxy-3-benzylidene camphor, 3'5'-dimethoxy-4'-hydroxy-3-benzylidene camphor, and 3',4',5'-trihydroxy-3-benzylidene camphor.
Dependencies are inferred from the claim text.