Back to results
US 5,177,259 AGranted
Diarylalkanoids having activity as lipoxygenase inhibitors
AssigneeWarner-Lambert Company
InventorsDavid T. Connor, Daniel L. Flynn
Life of this patent
Estimating the term…
Abstract
The present invention is novel diarylalkanoids having activity as lipoxygenase inhibitors, novel pharmaceutical compositions therefor, and novel methods of use in treating asthma, allergies, cardiovascular diseases, migraines, psoriasis and immunoinflammatory diseases for diarylalkanoids. The compounds of this invention are also useful as cytoprotective agents.
Claims1
Benzeneacetic acid, 4-[[4-(4-hydroxy-3,5-dimethoxyphenyl)-2-oxo-3-butenyl]oxy]-, (E)-,
- benzeneacetic acid, 3-[2-oxo-3-(triphenylphosphoranylidene)-propoxy]-, methyl ester,
- benzeneacetic acid, 4-[[4-(4-hydroxy-3-methoxyphenyl)-2-oxo-3-butenyl]oxy]-, (E)-,
- benzeneacetic acid, 4-[[4-(3,5-dibromo-4-hydroxyphenyl)-2-oxo-3-butenyl]oxy]-, (E)-,
- benzeneacetic acid, 4-[[4-4-hydroxy-3,5-dimethylphenyl)-2-oxo-3-butenyl]oxy]-, (E)-,
- 3-buten-2-one, 4-(3,5-dichloro-4-hydroxyphenyl)-1-phenoxy-, oxime,
- benzeneacetic acid, 4-[[4-[[4-[3,5-bis(1,1-dimethylethyl)-4-hydroxyphenyl]-2-oxo-3-butenyl]oxy ]-, (E)-,
- 3-buten-2-one, 4-(4-hydroxy-3-methoxyphenyl)-1-(phenylthio)-, oxime,
- 3-buten-2-one, 4-(4-hydroxy-3-methoxyphenyl)-1-(phenylthio)-, oxime (E)-,
- benzeneacetic acid, 3-[[4-(4-hydroxy-3,5-dimethoxyphenyl)-2-oxo-3-butenyl]oxy]-, (E)-,
- benzeneacetic acid, 4-[4-(3,5-dibromo-4-hydroxyphenyl)-2-(hydroxyimino)-3-butenoxy]-,
- 3-buten-2-one, 4-(4-hydroxy-3,5-dimethylphenyl)-1-phenoxy-, oxime,
- 3-buten-2-one, 4-(3,5-dibromo-4-hydroxyphenyl)-1-phenoxy-, oxime,
- 3-buten-2-one, 4-(3-bromo-4-hydroxy-5-methoxyphenyl)-1-phenoxy-, (E)-,
- 3-buten-2-one, 4-(3,5-dibromo-4-hydroxyphenyl)-1-phenoxy-, (E)-,
- benzeneacetic acid, 3-[[4-(4-hydroxy-3,5-dimethoxyphenyl)-2-oxo-3-butenyl]oxy]-, methyl ester,
- 3-buten-2-one, 4-(3,5-dichloro-4-hydroxyphenyl)-1-phenoxy-, (E)-,
- benzeneacetic acid, 4-[[4-(3,5-dibromo-4-hydroxyphenyl)-2-oxo-3-butenyl]oxy]-, methyl ester,
- 3-buten-2-one, 4-(4-hydroxy-3,5-dimethylphenyl)-1-phenoxy-, (E)-,
- benzeneacetic acid, 4-[[4-(4-hydroxy-3,5-dimethylphenyl)-2-oxo-3-butenyl]oxy]-, methyl ester (E)-,
- benzeneacetic acid, 3-[[4-(3,5-bis(1,1-dimethylethyl)-4-hydroxyphenyl)-2-oxo-3-butenyl]oxy]-, methyl ester (E)-,
- benzeneacetic acid, 4-[4-[3,5-bis(1,1-dimethylethyl)-4-hydroxyphenyl]-2-(hydroxyimino)-3-buten oxy]-, methyl ester,
- 3-buten-2-one, 4-(3-bromo-4-hydroxy-5-methoxyphenyl)-1-phenoxy-, oxime.
19 more elements
Dependencies are inferred from the claim text.