Methods and compositions for diagnosing chronic immune thrombocytopenic purpura
AssigneeThe Scripps Research Institute
InventorsMark H. Ginsberg, Robert McMillan, Edward F. Plow
Life of this patent
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Abstract
A polypeptide consisting essentially of an amino acid residue sequence selected from the group consisting of: Tyr-His-Asp-Arg-Lys-Glu-Phe-Ala-Lys-Phe-Glu-Glu-Glu-Arg-Ala- Arg-Ala-Lys-Trp-Asp-Thr-Ala-Asn-Asn; SEQ ID No 1 and Ala-Asn-Asn-Pro-Leu-Tyr-Lys-Glu-Ala-Thr- Ser-Thr-Phe-Thr-Asn-Ile-Thr-Tyr-Arg-Gly-Thr, SEQ ID No 2.
Claims5
A purified polypeptide consisting essentially of an amino acid residue sequence selected from the group consisting of:
- Tyr-His-Asp-Arg-Lys-Glu-Phe-Ala-Lys-Phe-Glu-Glu-Glu-Arg-Ala-Arg-Ala-Lys-Trp -Asp-Thr-Ala-Asn-Asn;
- SEQ ID NO 1 and
- Ala-Asn-Asn-Pro-Leu-Tyr-Lys-Glu-Ala-Thr-Ser-Thr-Phe-Thr-Asn-Ile-Thr-Tyr-Arg -Gly-Thr, SEQ ID NO 2.
A purified polypeptide consisting essentially of an amino acid residue sequence of the formula:
- Tyr-His-Asp-Arg-Lys-Glu-Phe-Ala-Lys-Phe-Glu-Glu-Glu-Arg-Ala-Arg-Ala-Lys-Trp -Asp-Thr-Ala-Asn-Asn-Ala-Asn-Asn-Pro-Leu-Tyr-Lys-Glu-Ala-Thr-Se r-Thr-Phe-Thr-Asn-Ile-Thr-Tyr-Arg-Gly-Thr, SEQ ID NO 3.
A purified polypeptide consisting of an amino acid residue sequence of the formula:
- NH.sub.2 -Tyr-His-Asp-Arg-Lys-Glu-Phe-Ala-Lys-Phe-Glu-Glu-Glu-Arg-Ala-Arg-Ala-Lys-T rp-Asp-Thr-Ala-Asn-Asn-Ala-Asn-Asn-Pro-Leu-Tyr-Lys-Glu-Ala-Thr-Ser-Thr-Phe- Thr-Asn-Ile-Thr-Tyr-Arg-Gly-Thr-COOH, SEQ ID NO. 3.
Dependencies are inferred from the claim text.