4-amino substituted phenoxyalkyl carboxylic acid, ester, and alcohol derivatives as antihypercholesterolemic and antiatherosclerotic agents

A compound selected from the group consisting of:

• 5-[2,5-Dimethyl-4-[[(4-methylphenyl)-sulfonyl]amino]phenoxy]-2,2-dimethylpe ntanoic acid, methylester;
• 5-[4-[(Hexadecylsulfonyl)amino]-2,5-dimethylphenoxy]-2,2-dimethylpentanoic acid, methyl ester;
• 5-[2,5-Dimethyl-4-[[(phenylmethyl)sulfonyl]-amino]phenoxy]-2,2-dimethylpent anoic acid, methyl ester;
• 5-[4-[[(4-Fluorophenyl)sulfonyl]amino]-2,5-dimethylphenoxy]-2,2-dimethylpen tanoic acid, methyl ester;
• 5-[2,5-Dimethyl-4-[(2-naphthalenylsulfonyl)-amino]phenoxy]-2,2-dimethylpent anoic acid, methyl ester;
• 5-[4-[[(2,5-Dichlorophenyl)sulfonyl]amino]-2,5-dimethylphenoxy]-2,2-dimethy lpentanoic acid, methyl ester;
• 2,2-Dimethyl-5-[2,5-dimethyl-4-[[(2,4,6-trimethylphenyl)sulfonyl]amino]phen oxy]pentanoic acid, methyl ester;
• 5-[4-(Benzoylamino)-2,5-dimethylphenoxy]-2,2-dimethylpentanoic acid, methyl ester;
• 5-[2,5-Dimethyl-4-[(methylsulfonyl)amino]-phenoxy]-2,2-dimethylpentanoic acid, methyl ester;
• 5-[4-[[(4-Methoxyphenyl)sulfonyl]amino]-2,5-dimethylphenoxy]-2,2-dimethylpe ntanoic acid, methyl ester;
• 5-[4-[[[(2,4-Difluorophenyl)amino]carbonyl]-amino]-2,5-dimethylpenoxy]-2,2- dimethylpentanoic acid, methyl ester;
• 5-[4-[[[[2,6-Bis(1-methylethyl)phenyl]amino]-carbonyl]amino]-2,5-dimethylph enoxy]-2,2-dimethylpentanoic acid, methyl ester;
• and
• 5-[2,5-Dimethyl-4-[[(phenylamino)-thioxomethyl]amino]phenoxy]-2,2-dimethylp entanoic acid, methyl ester.