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US 5,177,004 AGranted
Enzymatic deacylation of acyl-aminosorboses
AssigneeBayer Aktiengesellschaft
InventorHermann Schutt
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Abstract
The present invention relates to an improved process for the preparation of 1-desoxynojirimycin. 1-Desoxynojirimycin can be reacted by alkylation on the nitrogen atom to give various saccharase inhibitors which are used therapeutically in the treatment of diabetes mellitus.
Claims1
A process for preparing aminosorbose comprising enzymatically deacylating N-phenylacetyl-aminosorbose with pencillin acylase at a pH of from about 8 to 9.5.
Dependencies are inferred from the claim text.