Use of a stent with the capability to inhibit malignant growth in a vessel such as a biliary duct
AssigneeMedical Innovative Technologies R&D Limited Partnership
InventorsRobert E. Fischell, Tim A. Fischell
Life of this patent
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Abstract
It is well known that radiation therapy can reduce the proliferation of rapidly growing cancer cells is a malignant tumor. The present invention utilizes a radioisotope which is integral to a stent which can irradiate the tissue in close proximity to the implantation site of the stent in order to reduce the rapid growth of malignant cells in a vessel, such as a bile duct while simultaneously maintaining vessel patency. The radioisotope could be place inside the stent, alloyed into the metal from which the stent is made, or preferably, it can be coated onto the stent's exterior surface.
Claims11
A stent comprising a generally tubular structure whose external surface is adapted to engage the wall of a human vessel, said stent being patent throughout its entire interior length and being formed from a radioactive material which is outwardly, radially expandable after insertion into a vessel of the human body, the radioactive material being adapted to be imbedded into the vessel wall so that the radioactive material preferentially emits radiation that can reduce the proliferation of malignant cells in the vessel wall that are in close proximity to said stent while simultaneously maintaining vessel patency.
A stent comprising a generally tubular, thin-walled structure adapted to be expanded radially outward against the wall of a vessel in a human body at least part of said stent being formed from a radioisotope material which is radially expandable, said radioisotope material being adapted to be imbedded into the vessel wall and further being adapted to decrease the rate of growth of the malignant cells while simultaneously maintaining vessel patency.
A method to simultaneously decrease growth of malignant cells in a vessel of a living body while maintaining vessel patency the method comprising:
- insertion of an expandable stent into the vessel, at least part of said stent being formed from a radioisotope material.
A method to simultaneously decrease growth of malignant cells in a vessel of a living body while maintaining vessel patency the method comprising:
- percutaneous insertion of a radioisotope source into a vessel by means of a catheter so that it is positioned at the site of the malignant cells, said radioisotope source being formed from a plurality of thin, wire-like, interconnected, radially expandable parts in the form of an expandable stent;
- radially expanding the radioisotope source so that it becomes imbedded in the vessel;
- and,
- removal of the catheter from the artery.
Dependencies are inferred from the claim text.