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US 5,175,320 AGranted
Fluorinated bile acid derivatives, processes for the preparation thereof and pharmaceutical compositions containing them
AssigneeGiuliani S.P.A.
InventorsRoberto Pellicciari, Aldo Roda, Giuliano Frigerio
Life of this patent
Estimating the term…
Abstract
Compounds of general formula I ##STR1## wherein R.sub.1 is hydrogen or hydroxy, and the hydroxy group at the 7-position can be either in .alpha. or .beta. configuration, are valuable in human therapy. Compounds I can be prepared by fluorination of the suitably protected 6.alpha.-hydroxy-7-keto-derivatives.
Claims1
3.alpha., 7.alpha.Dihydroxy-6-fluoro-5.beta.-cholan-24-oic acid of formula:
- ##STR5##
Dependencies are inferred from the claim text.