Process for preparing dihydrofuranone derivatives
AssigneeMitsui Petrochemical Industries, Ltd.
InventorsJunichi Imuta, Aiichiro Ori, Noriaki Kihara
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Abstract
The present invention provides a process for preparing dihydrofuranone derivative of the formula (I): ##STR1## wherein R.sup.1 and R.sup.3 are individually lower alkyl, and R.sup.2 is hydrogen or lower alkyl, by reacting a dihydrofuranone derivative of the formula(I): ##STR2## wherein R.sup.1 is as defined above, with a malonic acid derivative of the formula (II): ##STR3## wherein R.sup.2 and R.sup.3 are as defined above, in the presence of an alkalimetal alkoxide and/or an alkalimetal hydroxide.
Claims2
A process for preparing dihydrofuranone derivative of the formula (III):
- ##STR10## wherein R.sup.1 and R.sup.3 are individually lower alkyl, and R.sup.2 is hydrogen or lower alkyl, by reacting a dihydrofuranone derivative of the formula (I):
- ##STR11## wherein R.sup.1 is as defined above, with a malonic acid derivative of the formula (II):
- ##STR12## wherein R.sup.2 and R.sup.3 are as defined above, in the presence of an alkalimetal alkoxide and/or an alkalimetal hydroxide.
A process for producing a dihydrofuranone derivative of the formula (III):
- ##STR13## wherein R.sup.1 is a lower alkyl, R.sup.2 is hydrogen or a lower alkyl, and R3 is a lower alkyl, comprising reacting a dihydrofuranone derivative of the formula (I):
- ##STR14## wherein R.sup.1 is as defined above, with a malonic acid derivative of the formula (II):
- ##STR15## wherein R.sup.2 and R.sup.3 are as defined above, in a solvent in the presence of alkali metal alkoxide and/or alkali metal hydroxide, wherein said malonic acid derivative (II) is used in an amount of 0.5-1.2 mole per mole of said dihydrofuranone derivative (I), said alkali metal alkoxide and/or alkali metal hydroxide is used in an amount of 0.5-1.2 mole per mole of said dihydrofurnanone derivative (I), and the amount of said solvent is 5-30 times the weight of said dihydrofurnanone derivative (I).
Dependencies are inferred from the claim text.