Composition containing ephedrine base and alkyl salicylate for the delivery of ephedrine base in vapor form
OwnerNikhilesh N. Singhinventor
Life of this patent
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Abstract
A method of delivering ephedrine base in vapor form from a composition containing the ephedrine base and an alkyl salicylate. Methyl salicylate is the preferred alkyl salicylate. Optional ingredients in the composition include aromatic compounds such as menthol, camphor, and various other essential oils. The method is particularly useful in the treatment of nasal congestion and bronchial asthma. A preferred means of delivering the ephedrine base in vapor form in the treatment of nasal congestion and bronchial asthma is a vapor inhaler.
Claims21
A method of treatment of disorders of the nasal mucosa and the upper respiratory tract by administering to a human or animal in need of the treatment a therapeutically-effective amount of ephedrine base in vapor form released from a composition comprising from about 1% to about 99% by weight ephedrine base and from about 1% to about 99% by weight C.sub.1 -C.sub.5 alkyl salicylate.
A composition for use in delivering ephedrine base in vapor form for administration to a human, comprising:
- (1) from about 1% to about 99% by weight ephedrine base, and
- (2) from about 1% to about 99% by weight C.sub.1 -C.sub.5 alkyl salicylate.
A composition in the form of a viscous semi-solid for use in delivering ephedrine base in vapor form comprising:
- (1) from about 2% to about 10% by weight ephedrine base;
- (2) from about 5% to about 20% by weight alkyl salicylate selected from the group consisting of methyl salicylate, ethyl salicylate, amyl salicylate, and mixtures thereof;
- (3) from 0% to about 30% by weight aromatic compound;
- and
- (4) from about 40% to about 93% by weight petrolatum.
A composition for use in delivering ephedrine base in vapor form comprising:
- (1) from about 2% to about 25% by weight ephedrine base;
- (2) from about 5% to about 75% by weight C.sub.1 -C.sub.5 alkyl salicylate selected from the group consisting of methyl salicylate, ethyl salicylate, amyl salicylate, and mixtures thereof;
- (3) from 0% to about 93% by weight aromatic compound;
- and
- (4) from 0% to about 93% by weight of liquid vehicle selected from the group consisting of:
- (i) mineral oil;
- (ii) ethanol, isopropyl alcohol, and a mixture thereof;
- (iii) essential oil;
- and
- (iv) mixtures thereof. pg,27
A composition for use in delivering ephedrine base in vapor form comprising:
- (1) from about 1% to about 2% by weight ephedrine base;
- (2) from about 1% to about 2% by weight alkyl salicylate selected from the group consisting of methyl salicylate, ethyl salicylate, amyl salicylate, and mixtures thereof;
- (3) from 0% to about 5% by weight aromatic compound;
- and
- (4) from about 90% to about 96% by weight hardboiled candy composition.
Dependencies are inferred from the claim text.