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US 5,174,988 AGranted
Phospholipid delivery system
AssigneeScientific Development and Research, Inc.
InventorsAlan J. Mautone, Joel Klayman
Life of this patent
Estimating the term…
Abstract
A process to prepare lipid crystalline figures in fluorocarbon propellants for the delivery of therapeutically active substances which form amorphous films on delivery and which can be suspended in aqueous media to serve as a drug delivery system or, when used without therapeutically active substance, as an artificial tear.
Claims5
A process for preparing lipid crystals in combination with a therapeutically active substance comprising
- (a) admixing dipalmitoylphosphatidyl choline, one of the group of phospholipids known as fully saturated acyl chain phosphatidylcholines, and cholesteryl palmitate, in powder form, with a therapeutically active substance and one or more fluorocarbon propellants, said lipids being insoluble in the propellants;
- and
- (b) evaporating the propellants.
A process for preparing lipid crystals in combination with a therapeutically active substance comprising
- (a) admixing dipalmitoylphosphatidyl choline and cholesteryl palmitate, in powder form, with a therapeutically active substance and one or more fluorocarbon propellants, said lipids being insoluble in the propellants;
- and
- (b) evaporating the propellants.
Dependencies are inferred from the claim text.